In the context of migration, managing chronic diseases can sometimes be a major challenge for both patients and caregivers. Screening is not systematic, glycated haemoglobin may be overestimated, especially in populations of African origin, and the risk of type 2 diabetes occurs at lower body mass index, especially in South Asia. Despite the existence of recommandations, linguistic, sociocultural, administrative and economic barriers exist and contribute to discontinuation of care. Finally, fasting during Ramadan requires risk stratification and treatment adjustments. Culturally appropriate care and therapeutic education, as well as multidisciplinary teamwork, are necessary to ensure proper care.