Postsecondary institutions around the world are grappling with how best to respond to what is described as a crisis in student mental health, with urgent calls for evidence-based advocacy, campaigning, and global action. In response to this call to action, in this article we advocate for a stronger role for occupational therapy in supporting student mental health in postsecondary settings through the enactment of the Okanagan Charter: An International Charter for Health Promoting University and Colleges , which celebrated its tenth anniversary in 2025. We share examples of innovative occupational therapy services and developments from the United States and Ireland specifically addressing the growing mental health needs of postsecondary students; highlight advocacy efforts and international collaborations and offer suggestions for how occupational therapy practitioners can work to consolidate and expand this vibrant and necessary emergent practice area through the basic tenets of the Okanagan Charter: An International Charter for Health Promoting University and Colleges .